THE THYROXINE-LIKE ACTIVITY OF SOME NEW THYROXINE ANALOGUES IN AMPHIBIA

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The thyroxine-like activity of compounds structurally related to thyroxine.

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Structural analogues antagonistic to thyroxine.

Since many compounds related structurally in specific ways to metabolically important substances have been found to produce signs of deficiency of the analogous metabolite, Woolley (1) proposed that’ new series of pharmacological agents might be produced by altering the structures of vitamins or hormones in definite ways. It was considered possible that such inhibitory structural analogues coul...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1954

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)65427-4